Investors were concerned following North Korea's latest missile test over Japan, causing investors to be nervous about geopolitical tensions once more.
This nervousness contributed to a 1.2% decline in the FTSE 100 to 7,205. Also weighing on the index was weakness in its biggest constituent, Royal Dutch Shell (RDSB). The oil giant fell 2% to £21.37.
Compounding the problem was weakness elsewhere in the natural resources sector including many of the large mining companies. Anglo American (AAL), Glencore (GLEN) and Antofagasta (ANTO) were down by up to 1.8%.
Vodafone (VOD), which is the eleventh largest company in the FTSE 100 index, dipped 1.4% to 206.9p.
Brent crude oil was stable at $55.46 per barrel.
FTSE 100 RISERS AND FALLERS
Soft drinks bottler Coca-Cola HBC (CCH) nudged 1.1% lower to £25.79 on news that chief executive Dimitris Lois will take a leave of absence to undergo medical treatment.
FTSE 250 RISERS AND FALLERS
Investors raised a glass to budget-friendly pub chain JD Wetherspoon (JDW) after pre-tax profit before exceptional items rose to £102.8m in the 53 weeks to 30 July 2017, up from £80.6m in 2016.
A 4% increase in like-for-like sales supported the strong results as shares in JD Wetherspoon rallied 10.6% to £11.57.
JD Sports Fashion (JD.) entered a joint venture agreement with South Korean footwear retailer Shoemarker, but this failed to spark the share price at 379.4p.
Speciality pharmaceutical firm Indivior (INDV) was down 1.7% at 297.6p after its US subsidiary filed patent lawsuits against Dr Reddy's, Actavis, Par, Alvogen, Teva, and Mylan. The lawsuits were for infringement of a US patent relating to their respective proposed generic versions of Indivior's Suboxone product.
SMALL CAP RISERS AND FALLERS
Toy maker Character Group (CCT) struggled after the board fired finance director Mark Dowding due to a 'loss of confidence' in him. The company said joint managing director Kiran Shah will take over the group financial director role. Shares in the company fell 4.3% to 496.5p.
Nearly a fifth of logistics business DX's (DX.) value was wiped off after the company used an incorrect accounting policy for a lease incentive for one of its sites. Investors were frustrated that there will now be a £1.8m non-cash impact to underlying profit for the year to 30 June 2017.
Online estate agent Purplebricks (PURP) gained 3.9% to 405.6p on its formal launch in the US. It will debut in Los Angeles before extending across the state of California and other targeted key states.
Shares in The Gym Group (GYM) accelerated 6.6% to 215p after acquiring 18 gyms from Lifestyle Fitness for £20.5m.
Middle Eastern-themed restaurant business Comptoir (COM) reported a 'steady' performance despite challenging conditions in the sector. Sales were up 36.1% to £13.1m and gross profit rose 36.4% to £9.5m in the first half of 2017. Investors were not convinced Comptoir was past its troubles as the stock was flat at 16.8p.